12 June 2012
4 - 5pm
Venue: Ground Floor Seminar Room (G010), UniServices House, 70 Symonds Street, Auckland
A Bioengineering research seminar by Dr David Goldstone, Rutherford Discovery Fellow, School of Biological Sciences
Host genomes display evidence of prolonged and repeated exposure to retroviral pathogens. Consequently, cells have evolved an array of innate cellular responses that block and contain retroviral infection.
Dr Goldstone will present work towards understanding how two of these systems: (i) the post entry restriction factors Fv1 and Trim5α, and (ii) SamHD1, act to disrupt infection of a range of retroviruses including HIV.