Restriction factors – a cellular defence against retroviral infection (Video)  

(Seminars)

12 June 2012

4 - 5pm

Venue: Ground Floor Seminar Room (G010), UniServices House, 70 Symonds Street, Auckland

Dr David Goldstone

A Bioengineering research seminar by Dr David Goldstone, Rutherford Discovery Fellow, School of Biological Sciences

Host genomes display evidence of prolonged and repeated exposure to retroviral pathogens. Consequently, cells have evolved an array of innate cellular responses that block and contain retroviral infection.

Dr Goldstone will present work towards understanding how two of these systems: (i) the post entry restriction factors Fv1 and Trim5α, and (ii) SamHD1, act to disrupt infection of a range of retroviruses including HIV.

Watch the high-resolution version of this video.

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