MALDI imaging mass spectometry: A powerful tool for molecular tissue imaging  Download event as icalendar

(Seminars)

4 September 2012

3.30pm

Venue: Room 501.505, Level 5, Building 501, Faculty of Medical and Health Sciences, Grafton Campus

Contact info: Robyn McDonald

Contact email: r.mcdonald@auckland.ac.nz


Department of Molecular Medicine and Pathology seminar by Dr Angus Grey, Sensory and Motor Systems Group, Department of Optometry and Vision Science.

Have you ever wanted to get an image of the distribution of a target molecule or protein in tissue, but don’t have an antibody for it? MALDI IMS is an exciting new technology which combines mass spectrometry with histology to provide spatial information to map the tissue-wide distribution of multiple analytes (proteins/peptides/ lipids/small molecules) directly from a single tissue section. Generally, 10’s to 1000’s of native or post-translationally modified analytes are observed simultaneously in a single experiment, hence MALDI IMS is a uniquely powerful discovery tool. In this talk Gus will introduce the technology and discuss a range of projects to illustrate its efficacy and potential applications. With current utility already in oncology, endocrinology, ophthomology, anatomy and physiology, come along and see if this new technology is something that could be useful for your project.
 


 


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