Computational modelling of fetal cardiovascular development
Eligible for funding* | PhD
Our life before birth influences our later life cardiovascular health, with those born pathologically small having increased risk of cardiovascular disease. There are indicators of differences in cardiovascular structure and function at birth between appropriately grown and small babies, and a proposed biomechanical role of the placenta in driving these differences. However, whether these differences are biomarkers of later life cardiovascular health are unknown. This project will develop a data-driven computational model of blood flow and cardiovascular remodelling in fetal and early postnatal life, which will be guided by experimental data in a rodent model. This model will enable assessment of the hypothesised role of the placenta in later life health, and potentially to enable development of model based biomarkers of cardiovascular health that can be assessed at birth.
Desired skills
- Mathematical modelling
- Differential equations
- Programming (particularly in Python)
Contact and supervisors
For more information or to apply for this project, please follow the link to the supervisor below:
Contact/Main supervisor
Eligible for funding*
This project is eligible for funding but is subject to eligibility criteria & funding availability.
Page expires: 28 February 2026