A multi-center, longitudinal, observational study of children with achondroplasia.
The ACHieve Trial is a multi-center, longitudinal, observational study of children with achondroplasia. Achondroplasia is a bone growth disorder that causes disproportionate dwarfism (short stature as an adult).
We are enrolling 200 children worldwide, across 25-study sites in ten countries. Participants are infants and children with achondroplasia from birth to eight years of age.
The main objective of this study is to assess the rate of growth and body proportionality over time in children with achondroplasia. We will also assess the incidence and severity of comorbidities in children with achondroplasia.
What does the study involve?
Participants in the ACHieveTrial are seen every six months at our clinic at the Liggins Institute in Grafton, Auckland.
We measure body proportionality based on anthropometric parameters, including standing height (or equivalent), sitting height (or equivalent), body weight, head circumference, arm span, lower body segment, upper leg length, lower leg length, upper arm length, lower arm length, chest circumference, hand length and foot length.
We also assess the severity, timing, frequency, and medical intervention for comorbidities of achondroplasia.
How can I find out more?
To find out more or to enrol a child please contact the study coordinator, Kylie Briggs, on firstname.lastname@example.org